Trade name: Pimavanserin
Chemical name: 1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea
CAS No: 706779-91-1
Molecular Formula: C25H34FN3O2
Molecular Weight: 427.55
Appearance: White crystalline powder
Pimavanserin is a drug which acts as an inverse agonist on the serotonin receptor subtype 5-HT2A, with 10x selectivity over 5-HT2C, and no significant affinity or activity at 5-HT2B or dopamine receptors. It has been advanced to Phase III development as a treatment for patients with Parkinson's disease psychosis (PDP). Also, it targets to plays an important role in the treatment of various neuropsychiatric disorders.