(2-Acetyl-4-Methylpentyl)triMethylaMMoniuM Iodide/1069-62-1

Product Name:(2-Acetyl-4-Methylpentyl)triMethylaMMoniuM Iodide
Usage: Deutetrabenazine intermediate
Chemical Name: (2-Acetyl-4-Methylpentyl)triMethylaMMoniuM Iodide;2-acetyl-N,N,N,4-tetraMethylpentan-1-aMiniuM iodide
Cas No.: 1069-62-1

Product Details

Product Name:(2-Acetyl-4-Methylpentyl)triMethylaMMoniuM Iodide

Usage:  Deutetrabenazine intermediate

Chemical Name: (2-Acetyl-4-Methylpentyl)triMethylaMMoniuM Iodide;2-acetyl-N,N,N,4-tetraMethylpentan-1-aMiniuM iodide

Cas No.: 1069-62-1

 

Molecular Formula: C11H24INO

Molecular Weight: 313.2


Specifications: 

Appearance: white crystalline to off- white solid

Purity: 99.0%min


Expand Information:

Deutetrabenazine is a novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor indicated for the management of chorea associated with Huntington’s disease. It is a hexahydro-dimethoxybenzoquinolizine derivative and a deuterated Tetrabenazine. The presence of deuterium in deutetrabenazine increases the half-lives of the active metabolite and prolongs their pharmacological activity by attenuating CYP2D6 metabolism of the compound. This allows less frequent dosing and a lower daily dose with improvement in tolerability. Decreased plasma fluctuations of deutetrabenazine due to attenuated metabolism may explain a lower incidence of adverse reactions associated with deutetrabenazine. Deutetrabenazine is a racemic mixture containing RR-Deutetrabenazine and SS-Deutetrabenazine.


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